https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 An efficient continuous flow approach to furnish furan-based biaryls https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19862 t-butyl based palladium catalyst CatCart™ FC1032™. Deactivated aryl bromides and activated aryl chlorides were cross-coupled with 5-formyl-2-furanylboronic in the presence of (Bu)₄N⁺OAc⁻ using the bis-triphenylphosphine CatCart™ PdCl₂(PPh₃)₂-DVB. Initial evidence indicates the latter method may serve as a universal approach to conduct Suzuki cross-couplings with the protocol successfully employed in the synthesis of the current gold standard Hedgehog pathway inhibitor LDE225.]]> Wed 11 Apr 2018 17:16:27 AEST ]]> Small molecule inhibitors of the hedgehog signalling pathway as cancer suppressing agents https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27906 Mon 23 Sep 2019 12:18:54 AEST ]]>